Author

Antonio Esparza-Oros

Vividion Therapeutics (United States)ORCID 0009-0005-8334-470XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Aaron Nathan SneadiD· 1 shared Benjamin D. HorningiD· 1 shared Brian N. CookiD· 1 shared Chanyu Yue· 1 shared Cynthia BerryiD· 1 shared David S. WeinsteiniD· 1 shared Eileen TraniD· 1 shared Eric WaltoniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Aaron Nathan SneadORCID

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1 paper

Recent·Most cited

Cancer BiologySciencePeer-reviewedOct 9, 2025

Covalent inhibitors of the RAS binding domain of PI3Ka impair tumor growth driven by RAS and HER2

Joseph E. Klebba, Nilotpal Roy, Steffen M. Bernard…·Matthew P. Patricelli

The paper develops covalent inhibitors targeting the RAS binding domain of PI3Kα, showing efficacy against RAS and HER2-driven tumors without affecting glucose homeostasis.

16 citationstop 4%

mouseexperimental assay

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