Author

Chengze Huo

The Hong Kong University of Science and Technology (Guangzhou)ORCID 0009-0005-9550-7123Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Xiakun ChuiD· 2 shared Jun WangiD· 1 shared Shiqinrui XuiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 2 mutual co-author links

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2 shared papersBiophysics

Xiakun ChuORCID

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2 papers

Recent·Most cited

BiophysicsJournal of Chemical Theory and ComputationPeer-reviewedAug 4, 2026

Encounter-state over-anchoring governs productive PETase binding on PET surfaces

Chengze Huo, Jun Wang, Xiakun Chu

This study identifies post-adsorption alignment as a key bottleneck in PETase surface recognition and proposes a design strategy to improve productive binding.

1 citation

deep learningstatistical model

𝕏 PostBluesky

BiophysicsJournal of Chemical Information and ModelingPeer-reviewedSep 13, 2024

Unraveling the Interplay between Stability and Flexibility in Design of Polyethylene Terephthalate (PET) Hydrolases

Shiqinrui Xu, Chengze Huo, Xiakun Chu

This study investigates how stability and flexibility balance in PET hydrolases affects catalytic activity, finding that a thermophilic variant shows enhanced performance through structural flexibility.

22 citations

statistical model

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