Author

Casslynn W.Q. Koh

Agency for Science, Technology and ResearchORCID 0009-0006-0125-010XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2

Frequent Co-Authors

W.S. Sho GohiD· 2 shared Yeek Teck GohiD· 2 shared Alexandre H. ThiéryiD· 1 shared Christopher Hendra· 1 shared Donald Yuhui Sim· 1 shared Fei YaoiD· 1 shared Jing-Yuan ChooiiD· 1 shared Jonathan GökeiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBioinformatics

W.S. Sho GohORCID

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2 papers

Recent·Most cited

BioinformaticsNature BiotechnologyPeer-reviewedJul 19, 2021

Detection of differential RNA modifications from direct RNA sequencing of human cell lines

Ploy N. Pratanwanich, Fei Yao, Ying Chen…·Jonathan Göke

This paper introduces xPore, a method to detect differential RNA modifications from direct RNA sequencing, showing it identifies m6A sites with single base resolution and quantifies modification rate differences across cell lines.

308 citationstop 1%

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologyNucleic Acids ResearchPeer-reviewedAug 4, 2020

METTL4 catalyzes m6Am methylation in U2 snRNA to regulate pre-mRNA splicing

Yeek Teck Goh, Casslynn W.Q. Koh, Donald Yuhui Sim…·W.S. Sho Goh

This study identifies METTL4 as the methyltransferase responsible for m6Am modification in U2 snRNA, showing its role in regulating pre-mRNA splicing.

120 citationstop 3%

humanbulk RNA-seq

𝕏 PostBluesky