Author

Fei Yao

Agency for Science, Technology and ResearchORCID 0000-0002-1769-9140Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 2 Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 4 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:variant calling· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Jonathan GökeiD· 3 shared Alexandre H. ThiéryiD· 2 shared Chiea Chuen KhoriD· 2 shared Christopher Hendra· 2 shared Hwee Meng Low· 2 shared Mile ŠikićiD· 2 shared Patrick B. O. TaniD· 2 shared Ploy N. PratanwanichiD· 2 shared

Activity by Year

2021-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenomics

Jonathan GökeORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Integrative Analysis of Spatial Transcriptome and Connectome by SpaCon

Haichao Qu, Wenyuan Li, Fei Yao, Shijie Zhao, Junwei Han, Cirong Liu

SpaCon integrates spatial transcriptomics and connectomics to reveal gene-connectivity coupling in the cortico-thalamic circuit and improves connectivity prediction from gene expression.

bioRxiv · Dec 25, 2025 · PreprintNeuroscience

A Complete Telomere-to-Telomere Diploid Reference Genome for Indian Population

Prasad Sarashetti, Josipa Lipovac, Jia Qi, Ling Wang, Zhe Li, Lovro Vrček, Ying Chen, Fei Yao, YY Sia, Dehui Lin, Xinyi Zhang, Daniel Muliaditan, Hwee Meng Low, See Ting Leong, Chiea Chuen Khor, , Jianjun Liu

The paper presents a high-quality, gapless diploid reference genome for an Indian population, revealing extensive structural variation and improved performance for genomic analysis in South Asian samples.

bioRxiv · Jul 12, 2025 · PreprintGenomics

A systematic benchmark of Nanopore long read RNA sequencing for transcript level analysis in human cell lines

Ying Chen, N. Davidson, Yuk Kei Wan, Fei Yao, Yan Su, Hasindu Gamaarachchi, Andre Sim, Harshil Patel, Hwee Meng Low, Christopher Hendra, Laura Wratten, Christopher Hakkaart, Chelsea Sawyer, Viktoriia Iakovleva, Puay Leng Lee, , Jonathan Göke

This study benchmarks Nanopore long read RNA sequencing in human cell lines, showing improved isoform resolution compared to short reads.

Nature Methods · Mar 13, 2025Peer-reviewedGenomics

Detection of differential RNA modifications from direct RNA sequencing of human cell lines

Ploy N. Pratanwanich, Fei Yao, Ying Chen, Casslynn W.Q. Koh, Yuk Kei Wan, Christopher Hendra, Polly S. Y. Poon, Yeek Teck Goh, Phoebe M. L. Yap, Jing-Yuan Chooi, Wee Joo Chng, Sarah Boon Hsi Ng, Alexandre H. Thiéry, W.S. Sho Goh, Jonathan Göke

This paper introduces xPore, a method to detect differential RNA modifications from direct RNA sequencing, showing it identifies m6A sites with single base resolution and quantifies modification rate differences across cell lines.

Nature Biotechnology · Jul 19, 2021Peer-reviewedBioinformatics