Author

Sarthak Joshi

Tata Institute of Fundamental ResearchORCID 0009-0006-0263-5829Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Research Focus:database / resource· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Ramanathan SowdhaminiiD· 2 shared Aditi PathakiD· 1 shared Aditya Seshadri· 1 shared Adwait Govind JoshiiD· 1 shared Ananya Sinha· 1 shared Deepthi S Ajith· 1 shared Dheemanth Reddy RegatiiD· 1 shared Dhwani Kumar· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBioinformatics

Ramanathan SowdhaminiORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintMar 31, 2026

HORI-EN: Atomic-level energetic profiling and higher-order network identification in protein structures

Sarthak Joshi, Ramanathan Sowdhamini

HORI-EN identifies cooperative stabilization networks in protein structures by integrating atomic-level energetic scoring with higher-order graph-theoretic analysis, showing improved performance in predicting mutational hotspots.

DOI 10.64898/2026.03.29.715065

protein structurestatistical model

𝕏 PostBluesky

BioinformaticsFrontiers in PharmacologyPeer-reviewedJan 22, 2026

GRAYU: Graph-based Database integrating Ayurvedic formulations, medicinal plants, phytochemicals and diseases

Sarthak Joshi, Aditi Pathak, Dheemanth Reddy Regati…·R Sowdhamini

GRAYU integrates Ayurvedic formulations, plants, phytochemicals, and diseases into a graph database to support drug discovery and therapeutic hypothesis generation.

3 citationstop 2%

experimental assaydatabase / resource

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BioinformaticsDatabasePeer-reviewedJan 1, 2025

GenDiS3 database: census on prevalence of protein domain superfamilies of known structure in the entire sequence database

Sarthak Joshi, Shailendu Mohapatra, Dhwani Kumar…·Ramanathan Sowdhamini

GenDiS3 provides a census of protein domain superfamilies' prevalence across sequence databases, using computational tools to link sequences to known structures and explore evolutionary and functional diversity.

DOI 10.1093/database/baaf035

protein sequencestatistical model

𝕏 PostBluesky