Author

Sidhardha Reddy Surkanti

ORCID 0009-0006-2082-6290Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Bhargava Chary BasangariiD· 2 shared Sriram Shravan SaligramiD· 2 shared Vani KondaparthiiD· 2 shared Vishnu Vardhan KasturiiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersBioinformatics

Bhargava Chary BasangariORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintFeb 24, 2026

OligoGraph: A novel geometric graph-based approach for siRNA efficacy prediction

Sriram Shravan Saligram, Vishnu Vardhan Kasturi, Sidhardha Reddy Surkanti…·Vani Kondaparthi

OligoGraph predicts siRNA efficacy using a graph-based deep learning model, outperforming existing methods on multiple datasets for both 19- and 21-nucleotide siRNAs.

DOI 10.64898/2026.02.23.707354

deep learningdrug response / drug discovery

𝕏 PostBluesky

BioinformaticsbioRxivPreprintFeb 17, 2026

RNAiSpline: A Deep learning model for siRNA efficacy prediction

Sidhardha Reddy Surkanti, Vishnu Vardhan Kasturi, Sriram Shravan Saligram…·Vani Kondaparthi

RNAiSpline predicts siRNA efficacy using deep learning with self-supervised pretraining and KAN, CNN, and Transformer Encoder, achieving high ROC-AUC and F1 scores.

DOI 10.64898/2026.02.14.705949

deep learningbenchmarking

𝕏 PostBluesky