Author

Changyuan Guo

Chinese Academy of Medical Sciences & Peking Union Medical CollegeORCID 0009-0006-2749-0435Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Binliang LiuiD· 1 shared Dongxu Ma· 1 shared Erfan Xie· 1 shared Guilai JiangiD· 1 shared Heng Cao· 1 shared Heng LiiD· 1 shared Hengyi XuiD· 1 shared Jiang Wu· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Binliang LiuORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 28, 2026

ctDNA Release Heterogeneity in Luminal Breast Cancer Revealed by Single-Cell Multi-Omics Spatial Analysis

Hengyi Xu, Pengming Pu, Binliang Liu…·Jiaqi Liu

The paper identifies cellular and spatial determinants of ctDNA release in HR+/HER2- breast cancer using single-cell multi-omics spatial analysis, linking tumor states, mutations, and immune interactions to ctDNA release patterns.

DOI 10.64898/2026.09.27.754855

humanscRNA-seq

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MicrobiologybioRxivPreprintFeb 8, 2025

Multi-Omics Analysis of Wound Microbiome and Staphylococcus aureus in Pressure Ulcer

Changyuan Guo, Guilai Jiang, Yuanyuan Li…·Heng Li

This study uses multi-omics approaches to analyze the wound microbiome and Staphylococcus aureus in pressure ulcers, revealing reduced microbial diversity, antimicrobial resistance, and biofilm formation characteristics.

1 citation

humanmetagenomics

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