Molecular BiologybioRxivPreprint
Structural basis of lipid-mediated gating in a two-pore domain potassium channel
Fumiya K. Sano, Go Kasuya, Kohei Yamaguchi…·Osamu Nureki
This study presents the cryo-EM structure of TOK1, revealing its unique domain architecture and lipid-mediated gating mechanism through structural and functional analyses.
DOI 10.1101/2025.11.12.688043