GenomicsGigaSciencePeer-reviewed
Mutation Impact on mRNA Versus Protein Expression across Human Cancers
Yuqi Liu, Abdülkadir Elmas, Kuan‐lin Huang
The paper analyzes how mutations affect mRNA and protein expression in 953 cancer cases across six types, finding that 47.2% of somatic expression quantitative trait loci (seQTLs) impact protein levels, with some mutations showing disproportionate effects.
10 citations