Author

William G. Herbert

Mayo ClinicORCID 0009-0006-5834-5353Unclaimed ORCID profile · follow to get notified of new preprints

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Bioinformatics· 1

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Approach:deep learning· 1

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Marina R. S. Walther-AntonioiD· 1 shared Nicholas ChiaiD· 1 shared Paul A. JenseniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperBioinformatics

Marina R. S. Walther-AntonioORCID

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1 paper

Recent·Most cited

BioinformaticsPLoS Computational BiologyPeer-reviewedApr 22, 2026

Monotherapy cancer drug-blind response prediction is limited to intraclass generalization

William G. Herbert, Nicholas Chia, Paul A. Jensen, Marina R. S. Walther-Antonio

This paper quantifies the limitations of drug-blind prediction in cancer DRP models, showing that generalization relies on mechanistic overlap and that performance is more about dataset behavior than model behavior.

1 citation

bulk RNA-seqdeep learning

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