Tain Luquez

brisc is a multithreaded CPU toolkit for single-cell analysis that is faster and more reproducible than existing tools like Scanpy and Seurat.

The paper identifies cell-type-specific and continuous gene programs associated with Alzheimer's Disease across multiple racial and ethnic groups using single-nucleus RNA-seq and ATAC-seq.

ACE compares cell type annotations across studies, enabling users to align and analyze cell type classifications and metadata in health and Alzheimer's Disease research.

The paper examines immunosenescence trajectories in diverse populations, finding associations between immunological age and brain atrophy, while highlighting CMV status and genetic ancestry as key factors.