Author

Natalia Lukashchuk

AstraZeneca (United Kingdom)ORCID 0009-0006-6678-0072Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:perturbation response prediction· 1 Approach:statistical model· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Anne Ramsay BowdeniD· 1 shared Anton Mikhailovich SafonoviD· 1 shared Antonio MarraiD· 1 shared Ben O’LearyiD· 1 shared Bob T. LiiD· 1 shared Bradley Stephen WubbenhorstiD· 1 shared Chaitanya BandlamudiiD· 1 shared Dara S. RossiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

Anne Ramsay BowdenORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintFeb 5, 2024

Tumor suppressor heterozygosity and homologous recombination deficiency mediate resistance to front-line therapy in breast cancer

Anton Mikhailovich Safonov, Antonio Marra, Chaitanya Bandlamudi…·Pedram Razavi

The paper identifies how germline and somatic mutations interact to cause resistance to CDK4/6 inhibitors in breast cancer and proposes a sequential treatment strategy using PARP inhibitors.

18 citations

humanwhole-exome sequencing

𝕏 PostBluesky

GenomicseLifePeer-reviewedMay 22, 2020

Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance

Anne Ramsay Bowden, David A. Morales-Juarez, Matylda Sczaniecka-Clift…·Stephen P. Jackson

The paper assesses how p53 status affects CRISPR-Cas9 screen performance by comparing wild-type and TP53 knockout cells, showing that optimal design can still yield reliable results.

57 citations

humanCRISPR screen

𝕏 PostBluesky