Author

Matylda Sczaniecka-Clift

MRC Laboratory of Molecular Biology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:perturbation response prediction· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Abhilesh S DhawanjewariD· 1 shared Angelos GlynosiD· 1 shared Anne Ramsay BowdeniD· 1 shared Antony M. Hynes-Allen· 1 shared Cameron RyalliD· 1 shared David A. Morales-JuareziD· 1 shared Jelle van den AmeeleiD· 1 shared John Christopher ThomasiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Abhilesh S DhawanjewarORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

MitoPerturb-Seq identifies common and gene-specific single-cell responses to mitochondrial DNA depletion and heteroplasmy

Stephen P. Burr, Kathryn Auckland, Angelos Glynos, Abhilesh S Dhawanjewar, Cameron Ryall, W. Wei, Antony M. Hynes-Allen, Malwina Prater, Matylda Sczaniecka-Clift, Julien Prudent, Patrick Francis Chinnery, Jelle van den Ameele

Nature Structural & Molecular Biology · Apr 1, 2026Peer-reviewedGenomics

Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance

Anne Ramsay Bowden, David A. Morales-Juarez, Matylda Sczaniecka-Clift, Maria Martin Agudo, Natalia Lukashchuk, John Christopher Thomas, Stephen P. Jackson

The paper assesses how p53 status affects CRISPR-Cas9 screen performance by comparing wild-type and TP53 knockout cells, showing that optimal design can still yield reliable results.

eLife · May 22, 2020Peer-reviewedGenomics