Author

Michael L Magwira

University of ManchesterORCID 0009-0006-8516-7994Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:protein structure· 1 Approach:statistical model· 1 Organism:virus· 1

Frequent Co-Authors

James C HerzigiD· 1 shared Simon C. LovelliD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperEvolutionary Biology

James C HerzigORCID

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1 paper

Recent·Most cited

Evolutionary BiologybioRxivPreprintOct 27, 2025

Structural constraints acting on the SARS-CoV-2 spike protein reveal limited space for viral adaptation

James C Herzig, Michael L Magwira, Simon C. Lovell

This study analyzes structural constraints on the SARS-CoV-2 spike protein and finds limited change in constraint despite phenotypic evolution and no reduction in accessible substitutions over time.

DOI 10.1101/2025.10.27.684767

virusprotein structure

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