Author

Hannes Hentze

Agency for Science, Technology and ResearchORCID 0009-0006-9009-0995Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:phylogenetics / evolution· 1 Assay:proteomics· 1

Frequent Co-Authors

Bong Hwa Gan· 1 shared Darren Wan Teck Lim· 1 shared Dhananjay Umrani· 1 shared Greg Li· 1 shared Kantharaj Ethirajulu· 1 shared Lay Hoon Lee· 1 shared Maryam Yasin· 1 shared Pauline Yeo· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Bong Hwa Gan

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1 paper

Recent·Most cited

Cancer BiologyJournal of Cancer Science and Clinical TherapeuticsPeer-reviewedJan 1, 2024

Pharmacodynamic evaluation of AUM001/tinodasertib, an oral inhibitor of mitogen-activated protein kinase (MAPK)-interacting protein kinase 1, 2 (MNK1/2) in preclinical models and tissues from a Phase 1 clinical study

Bong Hwa Gan, Lay Hoon Lee, Reika Takeda…·Veronica Novotny-Diermayr

This paper evaluates the pharmacodynamic effects of AUM001/tinodasertib in preclinical models and human tissues from a Phase 1 study, showing dose-dependent inhibition of eIF4E phosphorylation in tumors and PBMCs.

DOI 10.26502/jcsct.5079248

humanmouse

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