Zhesi Zhang

The paper identifies miRNAs regulated by SOX10 depletion in uveal melanoma and shows their role in tumor-suppressive pathways.

miREA improves miRNA pathway analysis by incorporating miRNA-gene interactions, outperforming node-based methods in sensitivity and biological interpretability across cancer datasets.

This paper reviews the interplay between SOX10 and microRNAs in melanoma, identifying key network motifs and their role in regulating tumor plasticity and therapy resistance.