Carola Berking

The paper identifies miRNAs regulated by SOX10 depletion in uveal melanoma and shows their role in tumor-suppressive pathways.

The paper identifies E2F transcription factors as potential druggable targets in uveal melanoma by analyzing SOX10's role and its downstream effects.

The paper identifies melanoma differentiation and immune exhaustion as predictors of tumor progression and therapy response in in-transit melanoma patients through multiomic profiling.

The paper identifies Clindamycin as a potential inhibitor of pyroptosis in tumor-associated macrophages by integrating network biology and pharmacophore modeling.

This paper reviews the interplay between SOX10 and microRNAs in melanoma, identifying key network motifs and their role in regulating tumor plasticity and therapy resistance.

The paper integrates transcriptomics data into agent-based models of cancer to identify therapy resistance scenarios.