Author

Po‐Liang Cheng

University of PennsylvaniaORCID 0009-0007-0046-0313Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 5 Assay:whole-genome sequencing· 5 Approach:statistical model· 4 Research Focus:GWAS / association mapping· 3 Research Focus:database / resource· 1 Research Focus:fine-mapping· 1 Research Focus:imputation· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Gerard D. SchellenbergiD· 5 shared Wan‐Ping LeeiD· 5 shared Beth A. DombroskiiD· 4 shared John J. FarrelliD· 4 shared Yuk Yee LeungiD· 4 shared Adam Christian NajiD· 3 shared Badri Narayan VardarajaniD· 3 shared Brian W. KunkleiD· 3 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersGenetic & Genomic Medicine

Gerard D. SchellenbergORCID

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5 papers

Recent·Most cited

Genetic & Genomic MedicineHuman Genetics and Genomics AdvancesPeer-reviewedJul 31, 2025

A Specialized Reference Panel with Structural Variants Integration for Improving Genotype Imputation in Alzheimer's Disease and Related Dementias (ADRD)

Po‐Liang Cheng, Hui Wang, Beth A. Dombroski…·Wan‐Ping Lee

The paper develops an imputation panel integrating structural variants for Alzheimer's disease and related dementias, improving genotype imputation and identifying new genetic associations.

DOI 10.1016/j.xhgg.2025.100487

humanwhole-genome sequencing

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Genetic & Genomic MedicineAlzheimer s & DementiaPeer-reviewedMay 1, 2025

Alzheimer's Disease Sequencing Project Release 4 Whole Genome Sequencing Dataset

Yuk Yee Leung, Wan‐Ping Lee, Amanda B. Kuzma…·Li‐San Wang

The paper provides a whole-genome sequencing dataset of 36,361 ADSP participants, including variant annotations, phenotypes, and a linkage disequilibrium panel for Alzheimer's Disease research.

36 citationstop 1%

humanwhole-genome sequencing

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Genetic & Genomic MedicineAlzheimer s & DementiaPeer-reviewedOct 20, 2024

Association of Common and Rare Variants with Alzheimer's Disease in over 13,000 Diverse Individuals with Whole-Genome Sequencing from the Alzheimer's Disease Sequencing Project

Wan‐Ping Lee, Seung Hoan Choi, Margaret G. Shea…·Gina Marie Peloso

The paper investigates the association of common and rare variants with Alzheimer's Disease in 13,371 diverse individuals using whole-genome sequencing, identifying significant genetic loci and population-specific associations.

28 citationstop 2%

humanwhole-genome sequencing

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Genetic & Genomic MedicineMolecular NeurodegenerationPeer-reviewedAug 16, 2024

Whole-Genome Sequencing Analysis Reveals New Susceptibility Loci and Structural Variants Associated with Progressive Supranuclear Palsy

Hui Wang, Timothy S. Chang, Beth A. Dombroski…·Wan‐Ping Lee

This study uses whole-genome sequencing to identify new genetic loci and structural variants associated with progressive supranuclear palsy, including novel signals in APOE and H1/H2 haplotype region variants.

30 citationstop 2%

humanwhole-genome sequencing

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Genetic & Genomic MedicinemedRxivPreprintSep 13, 2023

Structural Variation Detection and Association Analysis of Whole-Genome-Sequence Data from 16,905 Alzheimer's Diseases Sequencing Project Subjects

Hui Wang, Beth A. Dombroski, Po‐Liang Cheng…·Wan‐Ping Lee

The paper identifies structural variations in whole-genome sequencing data from 16,905 ADSP subjects and finds associations with Alzheimer's disease and related endophenotypes.

10 citations

humanwhole-genome sequencing

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