Hui Wang

This paper performs a large-scale GWAS meta-analysis of neuropathologic lesions in Alzheimer's disease and related dementias, identifying both known and novel genetic associations.

The paper develops an imputation panel integrating structural variants for Alzheimer's disease and related dementias, improving genotype imputation and identifying new genetic associations.

The paper provides a whole-genome sequencing dataset of 36,361 ADSP participants, including variant annotations, phenotypes, and a linkage disequilibrium panel for Alzheimer's Disease research.

This paper introduces a new framework for CNV association analysis in whole genome sequencing data, identifying additional CNVs linked to Alzheimer's Disease.

The paper identifies structural variations in whole-genome sequencing data from 16,905 ADSP subjects and finds associations with Alzheimer's disease and related endophenotypes.

GRAPE is a genomic relatedness detection pipeline that accurately classifies kinship degrees using preprocessing, IBD detection, and relationship estimation.

This study maps gene expression and developmental trajectories in zebrafish embryos using Stereo-seq and scRNA-seq, identifying spatial gene modules and signaling interactions.

This study identifies genes associated with different stages of Parkinson's disease pathogenesis using longitudinal blood transcriptome analysis and suggests candidate drugs for each phase.