Yichen Yan

The paper identifies optimal scaling laws between mRNA and protein levels that maximize cell fitness, showing a universal lower bound of 0.5 for the scaling exponent across organisms.

This study investigates bacterial cell volume growth and finds subdiffusive random growth with an anomalous exponent of ~0.27, attributed to cell wall viscoelasticity.

This study quantifies the fitness cost of gene expression by disentangling it into transcription and translation components using a resource competition model in yeast.

This study shows nonspecifically DNA-bound RNA polymerases in bacteria buffer free RNAP concentration, reducing crosstalk between rRNA and mRNA transcription, and are evolutionarily advantageous.