Author

Luis A. Gracia Mazuca

The University of Texas at El PasoORCID 0009-0007-1334-7758Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:long-read sequencing· 1 Approach:statistical model· 1

Frequent Co-Authors

Eda KoculiiD· 2 shared Jonathon E. MohliD· 2 shared Isaac S. WeislowiD· 1 shared Salvador Rodarte· 1 shared Samuel S. ChoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 8 mutual co-author links

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2 shared papersBiochemistry

Eda KoculiORCID

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2 papers

Recent·Most cited

BiochemistryBiochemistryPeer-reviewedMar 27, 2026

Direct RNA Sequencing Reveals Stress-Dependent and Pathway-Specific rRNA Modification Reprogramming During 50S Biogenesis

Luis A. Gracia Mazuca, Salvador Rodarte, Isaac S. Weislow…·Eda Koculi

The paper uses direct RNA sequencing to analyze rRNA modifications in E. coli ribosome assembly intermediates and mature subunits, showing stress-dependent reprogramming of specific modifications.

1 citation

E. colilong-read sequencing

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BiochemistryBiochemistryPeer-reviewedJun 23, 2025

Post-transcriptional Modifications of the Large Ribosome Subunit Assembly Intermediates in E. coli Expressing Helicase-Inactive DbpA Variant

Luis A. Gracia Mazuca, Jonathon E. Mohl, Samuel S. Cho, Eda Koculi

The paper develops a method to detect RNA post-transcriptional modifications in E. coli ribosomal RNA without chemical treatment, identifying modification incorporation times in ribosome assembly intermediates.

2 citations

E. colibulk RNA-seq

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