Liang Yu

linearPOA introduces a memory-efficient framework for Partial Order Alignment with linear space complexity, significantly reducing memory usage for long-read sequencing.

This paper introduces VeloVGI, a method for accurate RNA velocity estimation in batch scRNA-seq data, outperforming existing methods in various datasets.

The paper investigates circRNA structure and function, finding internal complementary base-pairing sequences and proposing an 'open-close effect' hypothesis for circRNA transitions.

This study shows NtrX, a nitrogen metabolism regulator, directly controls CtrA signaling network genes to regulate cell division in Sinorhizobium meliloti.