Alexandros Pontikas

This study identifies genetic correlations and pleiotropic loci between atopic dermatitis and five neuropsychiatric disorders, highlighting shared inflammatory pathways and potential drug targets.

The paper develops polygenic transcriptome risk scores (PTRSs) for atopic dermatitis using transcriptome-wide association studies and shows improved predictive accuracy when combined with traditional polygenic risk scores.

This study identifies 176 gene-tissue associations in atopic dermatitis using transcriptome-wide association analysis, highlighting novel genes involved in allergic reactions, skin barrier integrity, and inflammation.