Author

Isabella M Silvestri

Vanderbilt UniversityORCID 0009-0007-6613-8386Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Approach:diffusion model· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1

Frequent Co-Authors

Alex KangiD· 1 shared Amir MotmaeniD· 1 shared Andrew C. LuiD· 1 shared Asim K. BeraiD· 1 shared Brian CoventryiD· 1 shared Carolina MölleriD· 1 shared David A. BakeriD· 1 shared David JuergensiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Alex KangORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintSep 29, 2025

De novo design of phosphotyrosine peptide binders

Magnus S. Bauer, Jason Z. Zhang, Kejia Wu…·David A. Baker

This paper introduces RFD2-MI, a deep learning framework for designing phosphotyrosine peptide binders, showing high specificity and affinity for phosphorylated targets.

4 citations

protein structuredeep learning

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