Author

Kazuki Shimamoto

The University of TokyoORCID 0009-0007-6803-7001Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Approach:contrastive learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Artem LysenkoiD· 1 shared Takuma ItoiD· 1 shared Tatsuhiko TsunodaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperBioinformatics

Artem LysenkoORCID

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1 paper

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BioinformaticsbioRxivPreprintMay 27, 2026

Training Strategy Optimization to Mitigate Shortcut Learning in Pan-Cancer Drug Response Prediction

Kazuki Shimamoto, Takuma Ito, Artem Lysenko, Tatsuhiko Tsunoda

This paper improves pan-cancer drug response prediction by addressing class imbalance and shortcut learning in domain adaptation models, achieving better performance in external patient cohorts.

DOI 10.64898/2026.05.23.725295

bulk RNA-seqstatistical model

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