Mary Sara McPeek

ADELLE is a statistical method for trans-eQTL mapping that outperforms existing approaches in detecting SNPs associated with multiple gene expression levels.

JASPER improves multitrait genetic association analysis in structured samples, finding more significant gene expression associations and pleiotropic effects.

This paper identifies a 'feast or famine' effect in genome-wide interaction studies that causes inconsistent type 1 error rates and proposes TINGA to correct for it, improving power and reliability.

BRASS is a permutation method for binary trait association mapping in structured samples, showing better type 1 error control than existing methods in simulations and applications to dog genome-wide association studies.

This paper introduces LMM-OPS, a linear mixed model method that improves calibration and power in genetic association studies with ancestry heterogeneity, demonstrating its effectiveness in a GWAS of white blood cell count in Hispanic/Latino women.