Author

Upamali Somathilake

Australian National UniversityORCID 0009-0007-7598-5675Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein design· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Christoph NitscheiD· 2 shared Alfred Morgenstern· 1 shared Frank BruchertseiferiD· 1 shared Lani J. DaviesiD· 1 shared Minghao ShangiD· 1 shared Santhanalaxmi KumaresaniD· 1 shared Sarah SpreckelmeyeriD· 1 shared Sven UllrichiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 18 mutual co-author links

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2 shared papersBioengineering

Christoph NitscheORCID

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2 papers

Recent·Most cited

BioengineeringAngewandte Chemie International EditionPeer-reviewedJun 4, 2026

Chelator-Free Radiometal Labeling Inside Engineered Affibodies

Lani J. Davies, Upamali Somathilake, Santhanalaxmi Kumaresan…·Christoph Nitsche

This paper describes a method to label affibodies with radiometals without using chelators, demonstrating stable metal binding and retention under various conditions.

DOI 10.1002/anie.6657079

protein structureexperimental assay

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BiochemistryCommunications ChemistryPeer-reviewedJun 27, 2024

Phage-Encoded Bismuth Bicycles: Instant Access to Targeted Bioactive Peptides

Sven Ullrich, Upamali Somathilake, Minghao Shang, Christoph Nitsche

This paper introduces a method to create bicyclic peptides using bismuth and arsenic in phage display, showing improved binding affinity over linear peptides.

31 citationstop 4%

proteomicsexperimental assay

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