Cancer BiologyJournal of Cell SciencePeer-reviewed
Nucleophosmin mutations lead to abnormal, but reversible, nucleoli architecture and aggregate formation - implications for NPM1-targeting therapies in AML
Martin A. Grundy, Kellie Lucken, Xiaomeng Xing…·Claire Seedhouse
This study shows that NPM1 mutations cause abnormal nucleoli structure and reversible aggregates in AML, suggesting new therapeutic targets.