Chemical Synthesis of Oligosaccharides Derived from Streptococcus pneumoniae Serotype 35B and D to Investigate Binding of Complement and Serum Factors
Ivan A. Gagarinov, Lin Liu, Francesco Torricella, John Glushka, Alpeshkumar K. Malde, Mark von Itzstein, Geert‐Jan Boons
This study synthesizes oligosaccharides from Streptococcus pneumoniae serotypes 35B and 35D to investigate their binding to complement and serum factors, revealing the role of O-acetylation in immune evasion and vaccine efficacy.
Journal of the American Chemical Society · Aug 6, 2025Peer-reviewedBiochemistry