Molecular BiologybioRxivPreprint
Roles of cellular senescence in driving bone marrow adiposity in radiation-and aging-associated bone loss
Abhishek Chandra, Anthony B. Lagnado, Joshua N. Farr…·Robert J. Pignolo
This study shows that cellular senescence drives bone marrow adiposity in radiation- and aging-associated bone loss through miR-27a upregulation and senolytic treatment reduces BMAT.
DOI 10.1101/2021.09.07.459232