BiophysicsbioRxivPreprint
A cascade of structural rearrangements positions peptide release factor II for polypeptide hydrolysis on the ribosome
Nina Michael, Bridget Y. Huang, Korak Kumar Ray…·Ruben L. Gonzalez
This study uses smFRET to analyze the conformational changes of RF2 on the ribosome, revealing structural rearrangements essential for polypeptide release and potential antibiotic targets.
DOI 10.1101/2025.03.09.642146