Author
Johns Hopkins UniversityORCID 0009-0008-6079-1138Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Aswathy Peethambaran Mallika, Meghraj Singh Baghel, Opal Sitzman…·Philip C. Wong
The paper shows that restoring multiple TDP-43 cryptic targets, not just Unc13a, rescues motor neuron disease in a mouse model of ALS.
Tianyu Cao, Meghraj Singh Baghel, Rashmi Thapa…·Philip C. Wong
This study shows that preventing cryptic splicing of UNC13A and other TDP-43 targets can preserve memory and reduce neuron loss in a TDP-43 knockout mouse model.
Meghraj Singh Baghel, Grace D. Burns, Aswathy Peethambaran Mallika…·Philip C. Wong
This study shows that TDP-43 dysfunction accelerates tauopathy, which primes co-filament assembly and dysfunction of TDP-43, exacerbating neuron loss in AD-LATE.
Aswathy Peethambaran Mallika, Jessica Yu, Opal Sitzman…·Philip C. Wong
AAV-PHP.eB-CTR gene therapy slows ALS progression and prevents paralysis in symptomatic mice by restoring TDP-43 function.