Dan Kaptijn

The paper identifies dual-acting regulatory QTLs and gene regulatory networks in immune cells to better understand how genetic variation influences disease susceptibility.

The paper performs a federated cis-eQTL meta-analysis across single-cell datasets to identify cell-type-specific genetic effects and link them to disease mechanisms.

The paper identifies highly cell-type-specific eQTLs using snRNA-seq data from brain and blood, showing that bulk analyses overestimate eQTL agreement.

The paper identifies co-eQTLs that alter gene co-expression relationships in specific cell types, linking these variants to immune disease associations.