Author

Yaochi Guo

Chinese Academy of SciencesORCID 0009-0009-1382-5355Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:protein design· 1 Assay:proteomics· 1

Frequent Co-Authors

Chenao LiiD· 1 shared Hui CheniD· 1 shared Jizhong LouiD· 1 shared Pengyuan Yang· 1 shared Xin Guan· 1 shared Yong ZhangiD· 1 shared

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2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBioinformatics

Chenao LiORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintJan 23, 2026

TCRAD: An End-to-End Framework for Antigen-Targeted T Cell Receptor Design

Chenao Li, Yaochi Guo, Xin Guan…·Jizhong Lou

TCRAD designs antigen-specific TCR CDR3β sequences using deep learning, achieving high accuracy in binder discrimination and structure prediction, with experimental validation showing 17.2% functional candidates.

DOI 10.64898/2026.01.21.700513

proteomicsdeep learning

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