Author
The Netherlands Cancer InstituteORCID 0009-0009-1407-3909Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Marius Messemaker, Bjørn P. Y. Kwee, Živa Moravec…·Ton N. Schumacher
The paper develops a validated TCR-pMHC database (TCRvdb) by assessing VDJdb entries with a high-throughput platform, finding only 50% of claims are functionally confirmed.
Daniel Álvarez Salmoral, Razvan Borza, Carmen Maiella…·Anastassis Perrakis A
AlphaBridge evaluates predicted biomolecular complexes using AlphaFold3 confidence metrics, clustering sequence motifs, and visualizing interfaces with 2D diagrams and interactive tools.
Michael Uckelmann, Daniel Álvarez Salmoral, Carmen Maiella…·Anastassis Perrakis A
The paper constructs an atlas of human multi-protein complexes by integrating computational structure predictions with genetic dependency data, identifying 354 high-confidence complexes including novel ones.
Maarten L. Hekkelman, Daniel Álvarez Salmoral, Anastassis Perrakis A, Robbie P. Joosten
DSSP 4 annotates protein secondary structure in a FAIR-compliant manner, introducing left-handed κ-helices and improving interoperability with mmCIF format.
Ida de Vries, Jitske Bak, Daniel Álvarez Salmoral…·Anastassis Perrakis A
The paper develops a comprehensive dataset of intrinsic disorder in human proteins, revealing that most proteins contain disordered regions with distinct characteristics and pathogenic mutation risks.