Alexander P. Wu

The paper introduces PhenoCompass, a model for virtual phenotypic screening that identifies novel PI3K/mTOR inhibitors from a large compound library.

The paper introduces GrID-Net, a graph neural network that detects causal locus-gene associations using cell-state parallax, uncovering noncoding mechanisms affecting 132 genes in schizophrenia.

PRESAGE predicts perturbation expression responses using gene embeddings and outperforms existing methods in functional evaluations.

Velorama infers causal gene regulatory networks using RNA velocity data, revealing TF interaction speeds and their links to disease.