Author

Finn MacLean

Fred Hutch Cancer CenterORCID 0009-0009-4100-1302Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:flow cytometry· 2 Organism:human· 2 Research Focus:differential expression· 1 Assay:imaging· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Adino Tesfahun TsegayeiD· 2 shared Ayumi SaitoiD· 2 shared Bhavna H. ChohaniD· 2 shared Irene Cruz TalaveraiD· 2 shared Jairam R. LingappaiD· 2 shared Jennifer M. LundiD· 2 shared Jessica B. GrahamiD· 2 shared Jessica L. Swarts· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Adino Tesfahun TsegayeORCID

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2 papers

Recent·Most cited

Genital herpes shedding episodes associate with alterations in the spatial organization and activation of mucosal immune cells

Finn MacLean, Rachael M. Zemek, Adino Tesfahun Tsegaye, Jessica B. Graham, Jessica L. Swarts, Sarah C. Vick, Nicole B. Potchen, Irene Cruz Talavera, Lakshmi Warrier, Julien Dubrulle, Lena K. Schroeder, Anna Elz, David Sowerby, Ayumi Saito, Katherine K. Thomas, , the Kinga Study Team

This study examines how HSV-2 shedding affects immune cell organization and gene expression in the vaginal mucosa, finding increased immune surveillance and potential tissue homeostasis mechanisms.

bioRxiv · Jun 24, 2025 · PreprintImmunology

Bacterial vaginosis-driven changes in cervicovaginal immunity that expand the immunological hypothesis for increased HIV susceptibility

Finn MacLean, Adino Tesfahun Tsegaye, Jessica B. Graham, Jessica L. Swarts, Sarah C. Vick, Nicole B. Potchen, Irene Cruz Talavera, Lakshmi Warrier, Julien Dubrulle, Lena K. Schroeder, Ayumi Saito, Corinne M. Mar, Katherine K. Thomas, Matthias Mack, Michelle C. Sabo, , for the Kinga Study Team

This study investigates how bacterial vaginosis alters cervicovaginal immunity, identifying immune cell changes that may contribute to increased HIV susceptibility.

Journal of Clinical Investigation · Mar 25, 2025Peer-reviewedImmunology