Anna Elz

This study identifies molecular and architectural changes in normal-adjacent field tissue in HNSCC that disrupt epithelial differentiation and may promote cancer development.

The paper identifies CD163+ monocytes and immature CD177+ neutrophils as markers of severe neurotoxicity after CD19 CAR T cell therapy through multi-omics profiling.

This study shows that overexpressing c-Jun in CAR-T cells enhances their ability to maintain PD-1+Tcf1+ stem-like cells in tumors and improves response to PD-L1 blockade.

This study compares commercial single-cell RNA sequencing platforms based on performance metrics and practical considerations.

This study examines how HSV-2 shedding affects immune cell organization and gene expression in the vaginal mucosa, finding increased immune surveillance and potential tissue homeostasis mechanisms.

This paper introduces a cell segmentation method using cell simulation to improve accuracy in single-cell spatial transcriptomics, showing better performance than existing methods in identifying tumor infiltrating immune cells.

This study introduces a method to generate high-quality single-nucleus transcriptomic data from FFPE samples using recent single-cell genomic technology.

This study analyzes the genetic diversity and differentiation of invasive silver carp across North America, identifying introgression and eDNA detection methods for monitoring their spread.