Author

Prapti Pokharel

Broad InstituteORCID 0009-0009-6316-5527Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:trajectory inference· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Cole TrapnelliD· 2 shared Davide CacchiarelliiD· 2 shared John L. RinniD· 2 shared Jonna GrimsbyiD· 2 shared Kenneth J. LivakiD· 2 shared Shuqiang LiiD· 2 shared Tarjei Sigurd MikkelseniD· 2 shared Alexander MeissneriD· 1 shared

Activity by Year

2014-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Cole TrapnellORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

GenomicsCell SystemsPeer-reviewedSep 1, 2018

Aligning single-cell developmental and reprogramming trajectories identifies molecular determinants of reprogramming outcome

Davide Cacchiarelli, Xiaojie Qiu, Sanjay R Srivatsan…·Cole Trapnell

The paper analyzes MYOD-mediated reprogramming of human fibroblasts using single-cell RNA-Seq to identify molecular determinants of reprogramming success and failure.

76 citationstop 4%

humanscRNA-seq

𝕏 PostBluesky

BioinformaticsNature BiotechnologyPeer-reviewedMar 23, 2014

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

Cole Trapnell, Davide Cacchiarelli, Jonna Grimsby…·John L. Rinn

The paper uses pseudotemporal ordering to analyze single-cell data and reveals dynamics and regulators of cell fate decisions.

7,318 citationstop 1%

scRNA-seqstatistical model

𝕏 PostBluesky