Author
Tarjei Sigurd Mikkelsen
10X Genomics (United States)ORCID 0000-0002-8133-3135Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2014-2021 · peak 1/yrCo-Author Collaboration Network
10 top collaborators · 23 mutual co-author links5 papers
Recent·Most cited
- GenomicsNature BiotechnologyPeer-reviewed
Direct capture of CRISPR guides enables scalable, multiplexed, and multi-omic Perturb-seq
Joseph M. Replogle, Thomas M. Norman, Albert Xu…·Britt Adamson
This paper introduces a method to directly capture CRISPR guides in single-cell RNA-sequencing libraries, enhancing Perturb-seq scalability and enabling multi-omic measurements.
- GenomicsCell SystemsPeer-reviewed
Aligning single-cell developmental and reprogramming trajectories identifies molecular determinants of reprogramming outcome
Davide Cacchiarelli, Xiaojie Qiu, Sanjay R Srivatsan…·Cole Trapnell
The paper analyzes MYOD-mediated reprogramming of human fibroblasts using single-cell RNA-Seq to identify molecular determinants of reprogramming success and failure.
- GenomicsNature CommunicationsPeer-reviewed✦ In-depth digest
Massively parallel digital transcriptional profiling of single cells
Grace X. Y. Zheng, Jessica M. Terry, Phillip Belgrader…·Jason H. Bielas
8-channel GemCode droplet barcoding captures ∼50% of loaded cells for 3′ mRNA counting, profiling 68k peripheral blood mononuclear cells and calling transplant chimerism from transcript variants.
- BioinformaticsNature BiotechnologyPeer-reviewed
The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells
Cole Trapnell, Davide Cacchiarelli, Jonna Grimsby…·John L. Rinn
The paper uses pseudotemporal ordering to analyze single-cell data and reveals dynamics and regulators of cell fate decisions.
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