Hugh C. McCullough

The paper develops a novel measure, CheSL Shannon diversity, to quantify carbohydrate complexity's effects on microbial diversity, interactions, and function in human fecal samples.

This study shows that C. difficile colonization in an in vitro model is not dependent on bile salts but relies on proline fermentation via Stickland pathway, with context-dependent effects.

The paper introduces a framework to model environment-dependent microbial interactions using growth kinetics and Lotka-Volterra models, validated with synthetic E. coli data.