Author

Yifang Chen

University of CambridgeORCID 0009-0009-6922-5332Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:chromatin & epigenetic regulation· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Assay:Hi-C· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Jan HuertasiD· 2 shared Jorge R. EspinosaiD· 2 shared Kieran O. RusselliD· 2 shared Maria Julia MaristanyiD· 2 shared Rosana Collepardo‐GuevaraiD· 2 shared David Farré-GiliD· 1 shared Huabin ZhouiD· 1 shared Jose Ignacio Perez LopeziD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

Jan HuertasORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiophysicsNature CommunicationsPeer-reviewedOct 3, 2026

Near-atomistic simulations reveal the molecular principles that control chromatin structure and phase separation

Kieran O. Russell, Yifang Chen, Jorge R. Espinosa…·Rosana Collepardo‐Guevara

This study introduces OpenCGChromatin, a model that simulates chromatin structure and phase separation, revealing how linker-DNA length and histone modifications affect chromatin organization.

3 citationstop 5%

ChIP-seqcryo-EM

𝕏 PostBluesky

BiophysicsbioRxivPreprintJun 24, 2026

A Spectrum of Free Energy Landscape Topologies Encodes Chromatin Polymorphism and Phase Separation

Yifang Chen, Jan Huertas, Maria Julia Maristany…·Rosana Collepardo‐Guevara

This paper maps the free-energy landscapes of chromatin structures and shows how linker DNA geometry and sequence modulate their topologies, influencing phase separation and structural polymorphism.

1 citation

Hi-Cstatistical model

𝕏 PostBluesky