GenomicsbioRxivPreprint
Please Mind the Gap: Indel-Aware Parsimony for Fast and Accurate Ancestral Sequence Reconstruction and Multiple Sequence Alignment including Long Indels
Clara Iglhaut, Jūlija Pečerska, Manuel Gil, Maria O. Anisimova
This paper introduces indelMaP, a method that improves ancestral sequence reconstruction and multiple sequence alignment by treating insertions and deletions as distinct evolutionary events, achieving high accuracy and speed for densely sampled datasets.