AmpliPhy improves gene trees by adding homologous sequences without affecting alignments
Dongwook Kim, Manuel Gil, Kazutaka Katoh, Christophe Dessimoz
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SIB Swiss Institute of BioinformaticsORCID 0000-0001-7089-6285Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
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Dongwook Kim, Manuel Gil, Kazutaka Katoh, Christophe Dessimoz
Gholamhossein Jowkar, Jūlija Pečerska, Manuel Gil, Maria O. Anisimova
The paper evaluates ARPIP's ability to reconstruct ancestral sequences with long indels, showing it preserves gap length distributions and captures deletion bias in mammalian proteins.
Clara Iglhaut, Jūlija Pečerska, Manuel Gil, Maria O. Anisimova
This paper introduces indelMaP, a method that improves ancestral sequence reconstruction and multiple sequence alignment by treating insertions and deletions as distinct evolutionary events, achieving high accuracy and speed for densely sampled datasets.
Ahmad Aghaebrahimian, Maria O. Anisimova, Manuel Gil
The paper introduces a multi-channel deep neural network for biomedical relation extraction that outperforms existing methods by leveraging textual and graph features.
Jūlija Pečerska, Manuel Gil, Maria O. Anisimova
This paper introduces a combinatorial optimization method to jointly infer multiple sequence alignments and phylogenetic trees under maximum likelihood, addressing computational limitations of existing approaches.
Ana Claudia Sima, Tarcisio Mendes de Farias, Erich Zbinden…·Christophe Dessimoz
The paper introduces a semantic model and federated approach to integrate heterogeneous biological databases, enabling joint queries across gene expression, orthology, and protein data sources.