Xiao Ding

VES predicts viral mutation fitness and evolutionary trajectories using a diffusion model trained on protein sequences, outperforming existing models in mutation fitting and forecasting future mutations.

This paper develops FutureFlu, a framework to predict influenza vaccine strains by quantifying viral fitness, showing improved accuracy compared to current methods.

This study models the antigenic evolution of seasonal influenza viruses using PREDAC and finds no need to update vaccine strains for the 2025 season.