Filippo Stocco

This paper introduces REXzyme, a model translating chemical reactions into enzyme sequences, and demonstrates its ability to generate active formate dehydrogenases for CO2 reduction.

ProtGPT3 is an open-source family of protein language models that enables controlled protein generation through alignment and prompting, showing effectiveness in generating functional proteins.

The paper analyzes a crowdsourced protein design competition, showing participants designed EGFR binders with varying affinities and highlighting challenges in benchmarking and experimental design.