Yet another de novo genome assembler

Abstract

Advances in sequencing technologies have pushed the limits of genome assemblies beyond imagination. The sheer amount of long read data that is being generated enables the assembly for even the largest and most complex organism for which efficient algorithms are needed. We present a new tool, called Ra, for de novo genome assembly of long uncorrected reads. It is a fast and memory friendly assembler based on sequence classification and assembly graphs, developed with large genomes in mind. It is freely available at https://github.com/lbcb-sci/ra.\n\nThis work has been supported in part by the Croatian Science Foundation under the project Single genome and metagenome assembly (IP-2018-01-5886), and in part by the European Regional Development Fund under the grant KK.01.1.1.01.0009 (DATACROSS). In addition, M.[S]. is partly supported by funding from A*STAR, Singapore.