Author

Hansen Chen

Central South UniversityPrimary ORCID profile (0000-0001-9506-6894 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Hansen CheniD2 papers · Stanford University

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:genome assembly· 1 Assay:long-read sequencing· 1 Approach:statistical model· 1

Frequent Co-Authors

Fan NieiD· 2 shared Feng LuoiD· 1 shared Jianxin WangiD· 1 shared Jianxin WangiD· 1 shared X J Shi· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 6 mutual co-author links

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2 shared papersBioinformatics

Fan NieORCID

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2 papers

Recent·Most cited

RefLA: Efficient reference-guided genome assembly from long reads

X J Shi, Hansen Chen, Fan Nie, Jianxin Wang

RefLA improves genome assembly speed and quality by using a reference genome to guide long-read assembly, outperforming both de novo and fast assemblers.

bioRxiv · Dec 25, 2025 · PreprintBioinformatics

HapBridge: A Methylation-Guided Approach for Correcting Switch Errors and Bridging Phased Blocks in Long-Read Phasing

Hansen Chen, Fan Nie, Feng Luo, Jianxin Wang

HapBridge improves haplotype phasing by correcting switch errors and bridging phased blocks using DNA methylation signals, achieving higher accuracy and contiguity in long-read sequencing.

bioRxiv · Nov 7, 2025 · PreprintBioinformatics