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bioRxivSystems BiologyPreprint

FALCONET: an R package to accelerate automatic visualisation of genome scale metabolic models

Hongzhong LuiD, Zhengming ZhuiD, Eduard Johannes KerkhoveniD, Jens NielseniD

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Abstract

SummaryFALCONET (FAst visuaLisation of COmputational NETworks) enables the automatic for-mation and visualisation of metabolic maps from genome-scale models with R and CellDesigner, readily facilitating the visualisation of multi-layers omics datasets in the context of metabolic networks.\n\nMotivationUntil now, numerous GEMs have been reconstructed and used as scaffolds to conduct integrative omics analysis and in silico strain design. Due to the large network size of GEMs, it is challenging to produce and visualize these networks as metabolic maps for further in-depth analyses.\n\nResultsHere, we presented the R package - FALCONET, which facilitates drawing and visualizing metabolic maps in an automatic manner. This package will benefit the research community by allowing a wider use of GEMs in systems biology.\n\nAvailability and implementationFALCONET is available on https://github.com/SysBioChalmers/FALCONET and released under the MIT License.\n\nContactnielsenj@chalmers.se\n\nSupplementary informationSupplementary data are available online.

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