TIANYU WU

The paper develops spatially-resolved models of the yeast galactose switch to show how intracellular organization affects regulatory dynamics.

MetaCarto automatically generates readable genome-scale metabolic maps by organizing reactions into biologically meaningful layouts, matching curated pathway representations and producing 2621 maps for 108 BiGG models.

A hybrid 4D whole-cell simulation of the minimal bacterium JCVI-syn3A integrates spatial reaction-diffusion, metabolism, polymer chromosome dynamics, and division across a complete 105-minute cell cycle.